CIP Online Cleaning System For Biopharmaceutical Freeze-drying Machine

Biopharmaceutical freeze-drying machine is widely used in a variety of drugs, traditional Chinese medicine, vaccines, biological agents, microorganisms, bacteria and strains, etc. The biopharmaceutical freeze-drying machine is used for human oral administration or injection into human and animal bodies for freeze-drying biological products, Chinese medicinal materials, drug injections, etc. If there is contamination, the light will cause infection, and the severe will even endanger life. Therefore, biopharmaceuticals need to pay attention to CIP online cleaning and SIP online disinfection and sterilization in all aspects of production to ensure the "sterile" requirements of the product. The CIP online cleaning system of biopharmaceutical freeze-drying machine is to ensure the quality requirements of medical freeze-drying products. The CIP online cleaning system of biopharmaceutical freeze-drying machine refers to the cleaning work of the system or equipment in the original installation position without any movement. The CIP online cleaning system is composed of nozzles, electric control valves, cleaning pipes, booster pumps, etc. The biopharmaceutical freeze-dryer with cleaning device is equipped with various nozzles and nozzles in the freeze-drying box, and the installation arrangement of the nozzles needs to ensure that every dead corner is cleaned with clean water (water that meets pharmaceutical requirements).

The CIP online cleaning system of biopharmaceutical freeze-drying machine is to inject cleaning water into the cleaning pipe through a pressurized pump, and then spray the box, partition, etc., at the same time, the spray nozzle runs up and down the plate layer, so as to eliminate the residual substances in the box and the plate layer that have not been cleaned. After cleaning in the box, Close each valve and drain water through the water ring vacuum pump. To achieve the purpose of cleaning, the biopharmaceutical online cleaning system needs to meet the requirements of GMP, the cleaning operation control is integrated in the control system, and the program control operation and time of the biopharmaceutical CIP online cleaning system is set by the operator according to the actual situation. According to the requirements of material use, the CIP online cleaning system or SIP online sterilization system of the biological freeze-drying machine is selected to ensure the production safety requirements.